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12 years of age is not recommended. For the treatment of plaque-type psoriasis. The amount of cream or ointment needed to cover a certain area can be calculated.

Guidelines recommend mild to moderate potency agents over potent corticosteroids, which should be used in short durations. Children and infants may absorb proportionally larger amounts of topical corticosteroids due to a larger skin surface area to body weight ratio, and therefore are more susceptible to developing systemic toxicity, especially with very-high-potency products. The normal inflammatory response to local infections can be masked by clobetasol. Apply to the affected scalp areas twice daily, once in the morning and once at night.

Instruct patients not to cover their head while the shampoo is on the scalp. Clobetasol is contraindicated in any patient with a history of corticosteroid hypersensitivity and hypersensitivity to clobetasol or any ingredients in the preparation.

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Wash hands before and after treatment. Apply directly to the affected area of the scalp. Cormax Ointment Consumer information is supplied by First Databank, Inc. Apply sparingly in a thin film and rub gently into affected area. In one double-blind clinical trial, 55 patients were treated up to 4 weeks with either clobetasol propionate or fluocinonide ointment in Orabase. Lower potency corticosteroids should be used on the face and intertriginous areas.

Purpura and skin lacerations that may raise the skin and subcutaneous tissue from deep fascia may be more likely to occur with the use of topical corticosteroids in geriatric patients. Absorption after topical application of clobetasol is increased in areas that have skin damage, inflammation, or occlusion, or in areas where the stratum corneum is thin such as the eyelids, genitalia, axillae, and face. The cycle was repeated as needed.

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As with other potent fluorinated topical corticosteroids, clobetasol should not be used to treat acne vulgaris, acne rosacea, or perioral dermatitis as clobetasol may aggravate these conditions. Because gastric ulceration and GI bleeding have been reported in patients taking deferasirox, use caution when coadministering with other drugs known to increase the risk of peptic ulcers or gastric hemorrhage including corticosteroids. Common side effects included oral candidiasis, hypogeusia, and burning sensation at the site of application. In one study of 35 patients, use of 0.

NOTE: Discontinue once control of the treated condition has been achieved. No stability data are currently available. Patients who fail to respond to clobetasol treatment after 1—4 weeks should be re-evaluated. 2 weeks, followed by a 1-week intermission.

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After the first 2 weeks, limit  use to localized lesions of moderate to severe plaque psoriasis that have not shown significant improvement. Because clobetasol is fluorinated and also contains a substituted 17-hydroxyl group, it is not metabolized in the skin. These reactions are listed in an approximately decreasing order of occurrence: burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infection, skin atrophy, striae, and miliaria. The entire skin surface of the average size adult will be covered by 30 g of topical steroid cream. Patients taking inadvertent doses of corticosteroids on the test day may exhibit abnormally high basal plasma cortisol levels and a decreased response to the test. Repeated application results in a cumulative depot effect in the skin, which may lead to a prolonged duration of action and increased systemic absorption.

Due to the fact that circulating levels are below the level of detection, the use of pharmacodynamic endpoints for assessing the systemic exposure of topical clobetasol is necessary. Safety and efficacy have not been established. SIDE EFFECTS Cormax Ointment is generally well tolerated when used for two-week treatment periods. A thin layer of Cormax Ointment should be applied with gentle rubbing to the affected skin area twice daily, once in the morning and once at night.

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Tell your doctor about any unusual or bothersome side effect. Limit treatment to 4 consecutive weeks and a maximum of 50 ml or 50 gram weekly. Clobetasol should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. In another small trial, clobetasol butyrate 0.

You should confirm the information on the PDR. Clobetasol preparations should not be applied to the face, groin, vagina, or axillae. Apply a thin layer to the affected skin areas twice daily, in the morning and in the evening.

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Safety and efficacy have not been established and use is not recommended by manufacturer. Both medications provided relief of pain and erythema, and decreased lesion size. Exacerbation of diabetes may occur with systemic absorption of the topical corticosteroid.

15 and 45 g tubes of ointment. Amounts greater than 50 g per week should not be used. If applied topically, care should be used to ensure the infant will not come into direct contact with the area of application, such as the breast.

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PHARMACOKINETICS Clobetasol is administered topically to the skin as a cream, gel, ointment, or topical solution. Apply to the psoriatic areas twice daily, once in the morning and once at night. Instruct patients not to bandage, cover, or wrap area in any way that may be occlusive. You may report side effects to FDA at 1-800-FDA-1088. Once daily, apply to dry, psoriatic scalp areas, leave in place for 15 minutes, then lather and rinse.

It is not intended to be a substitute for the exercise of professional judgment. After 15 minutes, add water, lather and rinse completely. Not for ophthalmic, oral, or intravaginal use. 50 g per week should not be used. Dry, scaly dermatoses may be best treated with emollient creams or ointments.

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Restrict application to the active lesions or affected areas and try to avoid normal surrounding skin. Limited reports have used topical clobetasol propionate cream as an alternative to intralesional corticosteroid injections. If unintended contact happens, the patient should rinse the exposed area well with water.

NOTE: Acute exudative inflammation, as occurs with poison ivy, may be best treated with a non-emollient cream or gel formulation, which are drying. Medications which affect pituitary or adrenocortical function, including all corticosteroid therapy, should be discontinued prior to and during testing with metyrapone. Generally not recommended for use on the face or intertriginous areas.

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NOTE: Clobetasol is not approved by the FDA for dental administration. If applying to the scalp, move the hair away from the affected area so that the foam can be applied. Do not use clobetasol propionate preparations with occlusive dressings.

At the cellular level, corticosteroids induce peptides called lipocortins. However, most dermatologists stress that topical corticosteroids can be safely used during lactation. Our Cormax Ointment Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. We do not record any personal information entered above. Do not wet hair prior to use.

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Call your doctor for medical advice about side effects. The most frequent adverse reactions reported for clobetasol propionate ointment have been local and have included burning sensation, irritation, and itching. In one study, the cream was applied once daily to the affected areas without occlusion for the treatment of atopic dermatitis.

Apply to the psoriatic scalp areas twice daily, once in the morning and once at night. The foam formulation of clobetasol is flammable. Topical corticosteroids, including clobetasol, should be used with caution in patients with diabetes mellitus. Children were closely monitored for adrenal suppression.