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Cushing syndrome has been reported in infants and adults as a result of prolonged use of topical clobetasol propionate formulations. Avoid using clobetasol topical to treat skin on your face, underarms, or groin area without your doctor’s advice.
Although the risk of serious side effects is low when clobetasol topical is applied to the skin, you should be aware of side effects that can occur if the medication is absorbed into your bloodstream. Cream and Ointment indicate that they are in the super-high range of potency as compared with other topical corticosteroids.
PEG 100 stearate, white wax, chlorocresol, sodium citrate, citric acid monohydrate, and purified water. Clobetasol propionate has the molecular formula C25H32CIFO5 and a molecular weight of 467.
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If no improvement is seen within 2 weeks, reassessment of the diagnosis may be necessary. If HPA axis suppression is noted, an attempt should be made to withdraw the drug, to reduce the frequency of application, or to substitute a less potent corticosteroid. Clobetasol topical may also be used for purposes not listed in this medication guide.
Use in pediatric patients under 12 years of age is not recommended. HPA axis suppression, Cushing syndrome, linear growth retardation, delayed weight gain, and intracranial hypertension have been reported in children receiving topical corticosteroids. If concomitant skin infections are present or develop, an appropriate antifungal or antibacterial agent should be used. Where can I get more information? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
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Do not use this medication over a large area of skin. Tell your doctor about any unusual or bothersome side effect. Topical steroid medicine can be absorbed through the skin, which may cause steroid side effects throughout the body. Although the risk of serious side effects is low when clobetasol topical is applied to the skin, you should be aware of side effects that can occur if the medication is absorbed into your bloodstream. It is not likely that other drugs you take orally or inject will have an effect on topically applied clobetasol topical. Clobetasol propionate has greater teratogenic potential than steroids that are less potent.
But many drugs can interact with each other. Cream and Ointment should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Talk with your doctor if you think your child is not growing at a normal rate while using this medication over a long treatment period. Cream and Ointment should be discontinued and appropriate therapy instituted.
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What is the most important information I should know about clobetasol topical? Pregnancy Teratogenic Effects Pregnancy Category C. Patients applying a topical steroid to a large surface area or to areas under occlusion should be evaluated periodically for evidence of HPA axis suppression. Do not cover treated skin areas with a bandage or other covering unless your doctor has told you to.
This includes prescription, over-the-counter, vitamin, and herbal products. To make sure you can safely take clobetasol topical, tell your doctor if you are allergic to any drugs, or if you have any type of skin infection. Your pharmacist can provide more information about clobetasol topical. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. This may be done by using the ACTH stimulation, A.
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An overdose of clobetasol is not expected to produce life-threatening symptoms. This medication should not be used for any disorder other than that for which it was prescribed. It is not known whether clobetasol topical will harm an unborn baby. The treated skin area should not be bandaged, otherwise covered, or wrapped so as to be occlusive unless directed by the physician. Avoid getting this medication in your eyes. Ointment were burning sensation, irritation, and itching in 0.
Do not use extra medicine to make up the missed dose. Systemic absorption of topical corticosteroids can produce reversible HPA axis suppression with the potential for glucocorticosteroid insufficiency after withdrawal from treatment. If you are treating the diaper area of a baby, do not use plastic pants or tight-fitting diapers. Children are more likely to absorb large amounts of a topical steroid through the skin. The following additional local adverse reactions have been reported with topical corticosteroids, and they may occur more frequently with the use of occlusive dressings and higher potency corticosteroids.
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How Much Do You Know About Psoriatic Arthritis? Cortico-steroids have been shown to be teratogenic in laboratory animals when administered systemically at relatively low dosage levels. Do not start a new medication without telling your doctor.
1 week in patients with eczema. Wash your hands before and after using clobetasol topical, unless you are using the medication to treat the skin on your hands. It reduces the actions of chemicals in the body that cause inflammation, redness, and swelling. Also avoid using this medication in open wounds. Do not use clobetasol topical on broken or infected skin.
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What should I avoid while using clobetasol topical? Apply a small amount to the affected area and rub it gently into the skin. There are no adequate and well-controlled studies of the teratogenic potential of clobetasol propionate in pregnant women.
Allergic contact dermatitis with corticosteroids is usually diagnosed by observing a failure to heal rather than noting a clinical exacerbation as with most topical products not containing corticosteroids. This medication is to be used as directed by the physician. If you use this medication long-term, your blood will need to be tested often.
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What should I discuss with my healthcare provider before using clobetasol topical? It is for external use only. Clobetasol topical is used to treat the inflammation and itching caused by a number of skin conditions such as allergic reactions, eczema, and psoriasis.
Also tell your doctor if you have diabetes. Do not use this medication on a child without medical advice. Can You Make Living With Psoriasis Easier? If no improvement is seen within 2 weeks, reassessment of diagnosis may be necessary. Report Problems to the Food and Drug Administration You are encouraged to report negative side effects of prescription drugs to the FDA.
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It is important to use clobetasol topical regularly to get the most benefit. Every effort has been made to ensure that the information provided by Cerner Multum, Inc. What are the possible side effects of clobetasol topical? If contact does occur, rinse with water.
Carcinogenesis, Mutagenesis, Impairment Of Fertility Long-term animal studies have not been performed to evaluate the carcinogenic potential of clobetasol propionate. Do not use this medication without telling your doctor if you are breast-feeding a baby. Less frequent adverse reactions were itching, skin atrophy, and cracking and fissuring of the skin. Because of a higher ratio of skin surface area to body mass, pediatric patients are at a greater risk than adults of HPA axis suppression and Cushing syndrome when they are treated with topical corticosteroids. Cream and Ointment in pediatric patients have not been established. Skip the missed dose if it is almost time for your next scheduled dose.
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Steroid absorption in children may cause unwanted side effects, or a delay in growth with long-term use. Your use of the content provided in this service indicates that you have read,understood and agree to the End-User License Agreement,which can be accessed by clicking on this link. Manifestations of adrenal suppression in children include low plasma cortisol levels and an absence of response to ACTH stimulation. Abnormalities seen included cleft palate and skeletal abnormalities. What other drugs will affect clobetasol topical? The mechanism of the anti-inflammatory activity of the topical steroids, in general, is unclear.
Recovery of HPA axis function is generally prompt upon discontinuation of topical corticosteroids. Covering the skin that is treated with clobetasol topical can increase the amount of medicine your skin absorbs, which may lead to unwanted side effects. While the number of patients is too small to permit separate analysis of efficacy and safety, the adverse reactions reported in this population were similar to those reported by younger patients. It is not known whether clobetasol topical passes into breast milk or if it could harm a nursing baby. Use the missed dose as soon as you remember. Contact your doctor if your condition does not improve within 2 weeks of using this medicine, or if you develop signs of a bacterial, fungal, or viral skin infection.